GETTING MY PKRRATING TO WORK

3B). R526 from your loop between αJ and αI anchors the C-terminal percentage of the activation loop by forming a salt bridge with E458 at the base of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the leading chain carbonyl of R413. The suggestion in the activation section is stabilized by a hydrogen bond among Y454 and E480 from αF.